One sentence summary – An eight-year-old girl in the UK with a rare genetic condition has become the first person to receive a transplant and no longer require immunosuppressant drugs for life, thanks to a groundbreaking stem cell transplant using her mother’s kidney and bone marrow at London’s Great Ormond Street Hospital (GOSH).
At a glance
- An eight-year-old girl in the UK has become the first person to receive a transplant and no longer require immunosuppressant drugs for life.
- Aditi Shankar underwent a successful kidney and bone marrow transplant at London’s Great Ormond Street Hospital (GOSH).
- The innovative stem cell transplant, using her mother’s kidney and bone marrow, allowed Aditi to discontinue immunosuppressants merely a month after the procedure.
- GOSH devised a unique treatment plan involving her mother’s bone marrow to correct her immune deficiency.
- This pioneering work at GOSH opens up new possibilities for transplant patients, demonstrating the potential for personalized treatment plans tailored to individual genetic conditions.
The details
In a groundbreaking medical achievement, an eight-year-old girl in the UK has become the first person to receive a transplant and no longer require immunosuppressant drugs for life.
Aditi Shankar, who suffers from the rare genetic condition known as Schimke’s immuno-osseous dysplasia, underwent a successful kidney and bone marrow transplant at London’s Great Ormond Street Hospital (GOSH).
The innovative stem cell transplant, using her mother’s kidney and bone marrow, allowed Aditi to discontinue immunosuppressants merely a month after the procedure.
Schimke’s immuno-osseous dysplasia affects both the immune system and kidneys, initially making Aditi ineligible for a kidney transplant.
However, GOSH devised a unique treatment plan involving her mother’s bone marrow to correct her immune deficiency.
Remarkably, Aditi’s body accepted her mother’s kidney as its own after receiving the bone marrow transplant, eliminating the need for lifelong immunosuppressant medication.
Prior to the transplant, Aditi faced numerous hospital visits for dialysis.
However, since the procedure, her health has significantly improved.
Now, she can partake in activities she previously couldn’t enjoy, such as swimming, singing, dancing, and playing on her trampoline.
Aditi’s mother expressed immense pride in being able to provide her daughter with both blood cells and a functioning kidney.
Aditi herself is overjoyed to have received her mother’s blood cells and kidney, allowing her to engage in activities like swimming without the need for a line.
This pioneering work at GOSH opens up new possibilities for transplant patients, demonstrating the potential for personalized treatment plans tailored to individual genetic conditions.
The successful outcome of Aditi’s transplant offers hope for others with similar immunodeficiency-related challenges, potentially improving their quality of life.
It is worth noting that while immunosuppressants are crucial for preventing organ rejection in transplant patients, they often entail side effects.
Aditi’s case represents a significant advancement in the medical field, highlighting the potential for reduced reliance on lifelong immunosuppressant drugs in specific circumstances.
This remarkable achievement at GOSH not only provides a new lease on life for Aditi but also paves the way for future advancements in organ transplantation and personalized medicine.
The success of this pioneering procedure brings hope and optimism for patients facing similar challenges, offering them a chance to live a healthier and more fulfilling life.
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| news.sky.com |
|---|
| – An eight-year-old girl in the UK has become the first person to receive a transplant and not need immunosuppressant drugs for life. |
| – Aditi Shankar, who has a rare genetic condition, received a new kidney and bone marrow from her mother. – |
| The stem cell transplant allowed her to stop taking immunosuppressants a month after the transplant. – Doctors at London’s Great Ormond Street Hospital (GOSH) performed the pioneering work. – Immunosuppressants are important for transplant patients to prevent organ rejection but can have side effects. – |
| Aditi was diagnosed with Schimke’s immuno-osseous dysplasia, a condition that affects the immune system and kidneys. – |
| The condition initially meant she couldn’t receive a kidney transplant. – GOSH developed a treatment plan involving her mother’s bone marrow to correct her immune deficiency. – Aditi’s body accepted her mother’s kidney as its own after receiving the bone marrow transplant. – |
| A month after the transplant, she was able to stop taking immunosuppressants. – Previously, Aditi spent a lot of time in the hospital receiving dialysis. |
| – Now, she can swim, sing, dance, and play on her trampoline. – |
| Aditi’s mother is proud to have been able to provide her daughter with blood cells and a kidney. |
| – Aditi is happy to have received her mother’s blood cells and kidney and can now go swimming without a line. |
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